For the first time in its fabled 40-year history, the showpiece State of Origin series is taking place at the end of the season due to the effects of COVID-19.
Origin has long been renowned as the toughest form of rugby league, but the intensity is set to go to new heights with the three matches taking place in consecutive weeks.
NSW are aiming for three straight series wins under coach Brad Fittler. Given Queensland's eight-year reign from 2006-13, the Blues have no shortage of motivation to stage their own dynasty.
The Maroons have old master Wayne Bennett back at the helm, with Kevin Walters relinquishing the clipboard following a four-year stint after being appointed coach of the Brisbane Broncos.
Walters will stay involved with the squad and Australian coach Mal Meninga, who coached Queensland during their unprecedented reign, has rejoined their ranks as an assistant coach.
For everything you need to know about the series, read on.
Locations and kick-off times Game one:
Wednesday, 4 November, 8.10pm at Adelaide OvalGame two:
Wednesday, 11 November, 8.10pm at ANZ Stadium, SydneyGame three:
Wednesday, 18 November, 8.10pm at Suncorp Stadium, Brisbane
Women's State of Origin The women's State of Origin clash will take place at Sunshine Coast Stadium on Friday, 13 November with kick-off set for 7.45pm.
The Blues have won the past four interstate fixtures.